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An important homologue of this gene is CSMD1
and acting in concert with PD-1 and CTLA-4 as an immune-checkpoint axis whose down-regulation on tumor or autoreactive lymphocytes promotes immune evasion or autoimmune pathologies such as SLE
The gene encodes the major membrane isoform
where it helps initiate and regulate immune responses
Purity > 95% as determined by Bis-Tris PAGE& HPLC Endotoxin <1EU/μg Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized powder Storage Buffer 20mM Tris
COX2 Recombinant Rabbit mAb,PBS Only (SDT-380-259) Biosimilar Antibody An important homologue of thisProduct Specification Host Rabbit Synonyms Prostaglandin G H synthase 2, Cyclooxygenase 2 (COX 2), PHS II, Prostaglandin H2 synthase 2 (PGH synthase 2; PGHS 2), Prostaglandin endoperoxide synthase 2, PTGS2 Immunogen Synthetic Peptide Location Nucleus, Membrane, Endoplasmic reticulum, Microsome Accession P35354 Clone Number SDT 380 259 Antibody Type Recombinant mAb Isotype IgG Application IHC P, ICC, IF, ICFCM Reactivity Hu Purification Protein A
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